I was curious to learn from you all about what you know about the medicinal uses of poison-dart frog venom. In the web article, "Poison Dart Frog" (at Poison Dart Frogs, Poison Dart Frog Pictures, Poison Dart Frog Facts - National Geographic), they said, "The medical research community has been exploring possible medicinal uses for some poison dart frog venom. They have already developed a synthetic version of one compound that shows promise as a painkiller." This is especially interesting to me, since my late wife died of ovarian cancer, and a common treatment for that disease is the intravenous infusion of Taxol, a compound extracted from the yew tree. This extraction and treatment process seems to be a possible parallel to the use of dart-frog venom referenced in this article.
Are any of you aware of the developments in this research? Are any of you involved in this research? If so, what is your experience in this area? Other questions that naturally occur to me are also:
- Is a chemical process documented yet whereby the pain-killing toxin can be manufactured without the use of a biological host, such as dart-frogs?
- Can the dart-frog community be a part of this research?
- What are the pain-killing mechanisms of the toxin?
- Is the dart-frog's resistance to the toxin reproducible in other organisms (as is observed in leimadophis epinephelus) -- i.e. if a biological host is needed for the production of the compound en masse, can another, less sensitive (non-endangered) organism be used instead of dart-frogs?
Thanks,
Mark
Are any of you aware of the developments in this research? Are any of you involved in this research? If so, what is your experience in this area? Other questions that naturally occur to me are also:
- Is a chemical process documented yet whereby the pain-killing toxin can be manufactured without the use of a biological host, such as dart-frogs?
- Can the dart-frog community be a part of this research?
- What are the pain-killing mechanisms of the toxin?
- Is the dart-frog's resistance to the toxin reproducible in other organisms (as is observed in leimadophis epinephelus) -- i.e. if a biological host is needed for the production of the compound en masse, can another, less sensitive (non-endangered) organism be used instead of dart-frogs?
Thanks,
Mark