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The 24 hours stated on the tube is an average time for average conditions. If your bead is more than about 1/4 thick you should plan on longer. If the area is poorly vented you should plan on longer. If the area is particularly humid, you should plan on longer. Pointing a small fan into the area will help.
If you can still smell ANY fumes, it is not fully cured. If it is still tacky, it is not fully cured.
As Randommind stated, if it is expired, it may never cure. If it was repeatedly frozen and thawed, it may never cure.
 

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The expiration date is good but still a little rubbery. Seems to be getting harder. There is still a slight smell. Would the smell be indicative of vapor and is this vapor toxic to the frogs?
Yes. Did you try pointing a small fan in there?
 

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I had a question regarding silicone as well. What type of silicone should we be using? Does it matter? I think I saw a pic of someone just using regular window silicone for the background. Is that ok, or should we only be using aquarium silicone only? It seems like this should be the case for the safety.
Research this thread. http://www.dendroboard.com/forum/parts-construction/35720-bio-seal.html After reading it I decided on GE silicone 1 and NOT GE silicone 2.
 

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Actual aquarium silicones should all be safe enough. The question is usually pointed more towards this. Which cheaper, non-aquarium silicones can be used?
 
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