The tank doesnt seem to have many hidding places, which would make them feel a little more safe in a new home...but that would have effected them in the first few days, not day five. Does the tank have any odors from silicone ect.? Looks like enough ventilation to avoid gas build up. How about the water in the misting system? Were they the only frogs who were in contact with the misting system? Do you have pics of the dead frogs? Had you noticed wrestling when they were in the shoe box?
I say put him under a spotlight and get some answers from him. If he resists, try the treatment.
I say put him under a spotlight and get some answers from him. If he resists, try the treatment.