I agree.I think it would be vet time for me if you have access to a good exotic vet.
Any issue if i get Silver sulfadiazine in the frogs eye? I doubt i will be able to successfully apply any medicine/cream without getting it in its eye due to the proximityDry out the tank and treat 1x/day using q-tip or syringe to apply medication at night.
I would not rely on the frog to fix itself. Something caused this, and rarely do infections go away on their own.